Erectile Dysfunction treatment cost comparison

Most patients being treated for ED start on oral medications (PDE5-I), such as Viagra™ or Cialis.™1 When those fail, penile injections are typically the next prescribed treatment.2 Over time, physicians may suggest a penile implant for those seeking a long-term, cost-effective treatment.2
Penile implants have been shown to be a more cost-effective long-term ED treatment2

*Disclaimer: This is based off a cost-effective analysis on erectile dysfunction management over a 10-year time period, not based off a single patient experience.
TM* Third party brands are property of their respective owners.

Typical Erectile Dysfunction Treatment Pathways

Here are some typical treatment pathways and estimated costs that ED patients may experience based on recent studies.
Most patients being treated for ED start on oral medications (PDE5-I), such as Viagra™ or Cialis™.1 When those fail, penile injections are typically the next prescribed treatment.2 Over time, physicians may suggest a penile implant for those seeking a long-term, cost-effective treatment.2
Penile implants are more cost effective than other ED treatments over time2
Tap on a treatment pathway. Then click on the years below for additional information.
Pathway 1
Oral Medication
Pathway 2
Pills to Injections
Pathway 3
Pills to Penile Implant
Year
$7685
$9865
$9865
$9865
$9865
$9865
$9865
$9865
$9865
$9,640*,5Total 10-year cost
$7685
$9865
$9865
$8,0895(12-month out-of-pocket cost for Alprostadil)
TBD
TBD
TBD
TBD
TBD
$10,829+*,5Total 10-year cost
$7685
$9865
$9865
$9865
$4,4021Penile implants are a long-term solution resulting in significant cost savings.
$0
$0
$0
$0
$8,128*,5Total 10-year cost
75% of men treated for erectile dysfunction are treated with ED pills first1
50% discontinue ED pills within a year3 due to concerns with lack of spontaneity, cost, chronic medication-dependent intercourse, long-term safety, perceived non-effectiveness, and more…3
77% of patients choose to move on to a more expensive brand of ED pills1
If pills are no longer successful, some patients try expensive penile injections, where complications are common and can add thousands to the cost of treating ED1
Penile implants are the most cost effective ED solution over a 10-year time frame2 and create significant opportunity for cost savings

Pathway 1: Oral medication (pills)

If you find success with ED pills, your out-of-pocket costs can average out to be over $9,500 through a 10-year period when using average monthly prescription rates.

Year
Annual Cost
First line oral medication
Second line oral medication
Total Cost
  • 50% discontinue ED pills within a year3 due to concerns with lack of spontaneity, cost, chronic medication-dependent intercourse, long-term safety, perceived non-effectiveness, and more…3
  • 77% of patients choose to move on to a more expensive brand of ED pills2

Pathway 2: Pills to injections

Of those who choose to use injections, 20% get priapism.1 56% discontinue use of injections within a year due to a desire for permanent modality of therapy, fear of needles, poor response, fear of complications, and more…6
Patients who struggle with priapism from injections generally will stop additional treatment.

Year
Annual Cost
Second line oral medication
(12-month out-of-pocket cost for Alprostadil)
(Complications can add thousands to the cost of treatment)
Total Cost
  • If pills are no longer successful, some patients try expensive penile injections, where complications are common and can add thousands to the cost of treating ED1
Priapism outpatient costs
72% of Priapism cases are outpatient2
10,829Total 10-year cost without Priapism
356Outpatient treatment cost for Priapism
11,185Total 10-year cost with Priapism
Priapism inpatient costs
28% of Priapism cases are inpatient2
10,829Total 10-year cost without Priapism
8,382Outpatient treatment cost for Priapism
19,211Total 10-year cost with Priapism

Pathway 3: Pills to Penile implant

Due to the risk associated with penile injections, most patients treat their ED with pills for around 5 years ahead of seeking a penile implant.7 Switching from pills to a penile implant at year 5 could save you thousands over the 10-year treatment timeline.

Year
Annual Cost
First line oral medication
Second line oral medication
Total Cost
  • Penile implants are the most cost effective ED solution over a 10-year time frame2 and create significant opportunity for cost savings.

*Disclaimer: This is based off a cost-effective analysis on erectile dysfunction management over a 10-year time period, not based off a single patient experience.
TM* Third party brands are property of their respective owners.

Important Safety Information

Titan® and Titan® Touch Inflatable Penile Prosthesis – Important Safety Information

A penile implant, also called a penile prosthesis, is concealed entirely within the body to address erectile dysfunction (impotence). The implant requires some degree of manipulation before and after intercourse to make the penis erect or flaccid.

Indications
The Titan and Titan Touch Inflatable Penile Prosthesis is indicated for male patients suffering from erectile dysfunction (impotence) who are considered to be candidates for implantation of a penile prosthesis.

Contraindications
The Titan and Titan Touch Inflatable Penile Prosthesis is contraindicated in patients who have one or more of the following:
(1) Patients with an active infection present anywhere in the body, especially urinary tract or genital infection.
(2) Patients with a documented sensitivity to silicone.
(3) Patients with unresolved problems affecting urination, such as an elevated residual urine volume secondary to bladder outlet obstruction or neurogenic bladder.
(4) Patients unwilling to undergo any further surgery for device revision.

Warnings
Implantation of the device may make latent natural erections, as well as other interventional treatment options, impossible. Men with diabetes or spinal cord injuries, as well as immunocompromised patients, may have an increased risk of infection associated with a prosthesis. Implantation of a penile prosthesis may result in penile shortening, curvature or scarring.

Precautions
Removal of an implanted prosthesis without timely reimplantation of a new prosthesis may complicate subsequent reimplantation or may make it impossible. MRI quality may be compromised if the area of interest is in the exact same area or relatively close to the position of the Titan, and Titan Touch IPP. Be sure to consult with your physician. Patients should discuss all available treatment options and their risks and benefits with their physician. Health conditions which hamper sexual activity, such as severe chest pain (angina), may prevent successful use of this device. The prosthesis should not be implanted in patients who lack the manual dexterity or strength necessary to operate the device. Trauma to the pelvic or abdominal areas, such as impact injuries associated with sports (e.g., bicycle riding), can result in damage of the implanted device and/or surrounding tissues. This damage may result in the malfunction of the device and may necessitate surgical correction, including replacement of the device. The device may be used in the presence of Peyronie’s disease.

Potential Complications
Penile implants are surgical solutions requiring a healing period that have risks associated with surgery such as scrotal swelling, auto-inflation, discomfort, angulation/curvature, swelling (edema), device malfunction, chronic pain, difficulty with ejaculation, transient urinary retention, fever, migration, patient dissatisfaction, infection at surgical site or wound, deflation, swelling of clotted blood or clear fluid (hematoma/seroma), wound leakage, bleeding, delayed wound healing, narrowing of the opening of the foreskin (phimosis), sensory loss, cylinder malfunction, formation of thick tissue (fibrous capsule formation), over/under inflation, erosion, scrotal reddening (erythema), genital change, and inguinal hernia. This treatment is prescribed by your physician. Discuss the treatment options with your physician to understand the risks and benefits of the various options to determine if a penile implant is right for you.

Caution: Federal law (USA) restricts this device to sale by or on the order of a physician.

PM-02124. 02.2021

1. Frederick, Luke R., Omer Onur Cakir, Hans Arora, Brian T. Helfand, and Kevin T. McVary. “Undertreatment of erectile dysfunction: claims analysis of 6.2 million patients.” The journal of sexual medicine 11, no. 10 (2014): 2546-2553. 2. Moses, Rachel A., Ross E. Anderson, Jaewhan Kim, Sorena Keihani, James R. Craig, Jeremy B. Myers, Sara M. Lenherr, William O. Brant, and James M. Hotaling. “Erectile dysfunction management after failed phosphodiesterase-5-inhibitor trial: a cost-effectiveness analysis.” Translational Andrology and Urology 8, no. 4 (2019): 387. 3. Jannini, Emmanuele A., and Stéphane Droupy. “Needs and expectations of patients with erectile dysfunction: an update on pharmacological innovations in phosphodiesterase type 5 inhibition with focus on sildenafil.” Sexual Medicine 7, no. 1 (2019): 1-10. 4. Kohn, Taylor P., Saneal Rajanahally, Wayne JG Hellstrom, Tung-Chin Hsieh, and Omer A. Raheem. “Global trends in prevalence, treatments, and costs of penile prosthesis for erectile dysfunction in men.” European Urology Focus (2021). 5. ED Treatment Pathway Good Rx Data for Pills and ICI. 6. Sundaram, Chandru P., William Thomas, Laurie E. Pryor, A. Ami Sidi, Kevin Billups, and Jon L. Pryor. “Long-term follow-up of patients receiving injection therapy for erectile dysfunction.” Urology 49, no. 6 (1997): 932-935. 7. Jorissen, Cedric, Helene De Bruyna, Evert Baten, and Koenraad Van Renterghem. “Clinical outcome: patient and partner satisfaction after penile implant surgery.” Current Urology 13, no. 2 (2019): 94-100.