NatureAbstract_1

Peyronie’s Disease is a condition marked by penile curvature, indentation, loss of penile length and pain (with or without an erection).38 These deformities of the penis can appear in men of all ages but is most commonly present in middle age men.40

The cause of Peyronie’s Disease is not well understood. In many cases, the disease is a result of inflammation and plaque formation after repeated trauma to the penis; for example, during sexual intercourse. When the penis heals from the trauma, scar tissue may form which could lead to curvature if that scar tissue can no longer stretch when trying to achieve an erection.38

Impact of Peyronie’s Disease

The impact of Peyronie’s Disease can be significant. It can cause one or more of the following conditions:

Penile deformity38
  • Resulting in indentation, narrowing or loss of length
  • Can interfere with the ability to engage in sexual activity and penetration
Psychological distress41
  • This condition has been recognized to affect a man’s psychological state including causation of depression and anxiety disorders. Appropriate diagnosis and treatment may require the help of an experienced medical professional.
Erectile Dysfunction38
  • Peyronie’s Disease is frequently linked to erectile dysfunction, which is the difficulty achieving or maintaining an erection.